Andor Technology (Andor), an Oxford Instruments company and world leader in scientific imaging and spectroscopy solutions, today announced the launch of Sona 4.2B-6, a new model in the ultrasensitive back-illuminated Sona microscopy camera series.
The Sona 4.2B-6 provides a superbly balanced combination of sensitivity, speed and resolution, making it perfectly suited to the needs of the most challenging microscopy applications. The new camera features a 4.2 Megapixel sensor format with a 6.5 µm pixel size. This format is suited to obtaining maximum resolution from the commonly used 60x and 40x objective lens magnifications.
This complements the existing Sona 4.2B-11 model, with a larger, 32 mm field of view and remains the camera of choice for imaging the largest possible sample area.
The Sona series represents the ultimate in sCMOS sensitivity, meaning signal to noise can be optimized under reduced illumination conditions, thus preserving accurate biology of living cells during extended measurement periods.
The Sona 4.2B-6 shares many of the key features that have made the existing Sona models so effective, namely the high sensitivity sensors with 95% quantum efficiency and exclusive permanent vacuum sealed sensor chambers with market leading cooling down to -45 °C.
Sona 4.2B-6 also features a Low Noise mode that uses correlated multi-sampling to reduce noise while maintaining frame rates and the low exposure times that are vital for studying live cells.
Dynamic cellular processes can be captured by the high-speed imaging capabilities – up to an impressive 74 fps for full-range 16-bit images. In addition, class leading linearity and dynamic range means that Sona provides the best available quantitative accuracy. Important for the growing number of applications that use measurements over time or change in fluorescence intensity levels to make determinations on rates, concentrations or spatial position such as FRET, ion signalling, gene expression analysis or localization based super-resolution.